Glutathione-S-Transferase & NAT2 - MicroTrace Minerals

Glutathione S-Transferase M1 (GSTM1)

GSTM1 is produced in the liver. Through conjugation with glutathione, it functions in the detoxification of environmental toxins and products of oxidative stress, electrophilic compounds, including carcinogens and therapeutic drugs.

Individuals with the GSTM1 */0 Genotype do not have this functioning enzymes and are at greater risk to develop carcinomas.

Glutathione S-Transferase T1 (GSTT1)

GSTT1 is found in lymphocytes and the liver, and is involved in the detoxification process of a variety of environmental chemicals, such as the ones used in polymer productions. Like all GST Enzymes, GSTT1 detoxifies cancer-causing chemicals as found in cigarette smoke. Approximately 38% of Caucasians show a complete lack of GTT1 activity. This group with the GSTT1 */0 Genotyp shows a high risk for carcinoma of the lung, breast and larynx.