Urine Metal Analysis (UMA)

Urine metal concentrations reflect excretion levels.

A comparison of an unprovoked (unchallenged) baseline urine with a Provocation urine following chelation allows an estimation regarding the body's metal load and the chelating agent's binding capability.

Our COMPARISON REPORT directly compares test results of repeat analysis results.

Baseline Urine - What we need to know

  • Elevated metal levels indicate immediate exposure. The renal system excretes metals without being provoked.
  • A low concentration on essential metals in urine may be caused by a reduced or inadequate dietary intake. It does not necessary indicate a nutritional deficiency.
  • If urine baseline results indicate low zinc excretion levels, supplementation is recommended before chelation therapy, esp. in the presence of low blood and hair zinc levels. 
  • To determine a nutritional deficiency, urine is not the ideal specimen

Provocation or Mobilisation Urine

  • The metal concentration in urine after provocation reflects the chelating agents ability to bind and eliminate certain metals via the renal system. Metals that have been stored in the body for some time are mobilized by the chelating agent and excreted with the urine.
  • To aid the physician in understanding test values, we have established reference ranges for specific chelators such as DMPS. We have called these Orientation Ranges. 
  • DMPS has a strong ability to bind with copper and will bind copper even in the presence of a low copper intake. The Orientation Range for copper takes this into account.
  • Certain chelating agents contain metals i.e. ZnDTPA contains zinc, and during the chelation process the zinc of the DTPA compound is exchanged for other metals. For ZnDTPA chelation test reports, zinc is not reported.